DECENTRALIZED MEDICINE #42: NATURE IS A CLEVER MEDICINE..........

After spending 18 months in the medical school library putting Nature's recipes together, this is the decentralized thesis I came up with.

Influenza is an electrical disease where nucleic acid joins nuclear DNA (see pic below). Ironically, every centralized scientist has no idea how endosymbiosis happens. Decentralized medicine knows that endosymbiosis was an electrical event during extreme hypoxia that forced the first domains of life to join forces to create a eukaryote. It was the first oncogenic event on Earth. As a result of that merger, evolution has to innovate heme proteins to protect themselves from the electrical stimulus of oxygen infusion to the environment.  I wonder when they will wake up to the reality that all of life is electrical because of oxygen.    

Apoptosis protects eukaroyotes from future cancer joining events. This was buried in CCO, a heme-based protein.

Oxygen is the only paramagnetic elemental gas in the periodic table. Oxygen changes the electrical resistance of everything with a membrane.  This became a big deal in the evolutionary story of heme biology and how we built our wireless connection to the sun from our mitochondria in the dangerous GOE event.

Oxygen can form oxides with certain materials (like metals or semiconductors). This is called oxidation. These oxide layers often have higher electrical resistance than the pure material, acting as insulators or semi-insulators. When oxygen binds to hemoglobin, it changes its electrical resistance. This can significantly change how electricity flows in devices with thin membranes, such as sensors or transistors.

Adsorption: In some cases, oxygen molecules adsorb onto the surface of a material or membrane. This can trap or scatter charge carriers (like electrons), increasing resistance. This effect is common in gas sensors, where oxygen exposure alters the conductivity of a membrane or thin film. Hb acts like this in a way, too.

Oxygen can also indirectly influence processes like ion transport or membrane potential through metabolic activity, which might affect measured resistance in specific contexts.

THE EVOLUTION OF THE GOE IS WHY ANYTHING THAT USES THE TCA CYCLE MUST SEE SUNRISE

So why do you have to see the sunrise before you can use the TCA cycle? Because the sunrise was here on Earth before oxygen was.  

This blockchain of events is what happened in the GOE. Before the GOE, nothing on Earth could have the TCA. The TCA cycle protects eukaryotic cells from the oxygen holocaust, which can cause cancer or tissue atrophy.

THE HUMAN BRAIN PROTECTS ITSELF FROM YOUR POOR LIGHT CHOICES BECAUSE IT FAVORS THE TCA CYCLE

The brain uses 20% of our cardiac output to run its TCA cycle and feed its oxygen addiction.  The red light in sunrise makes DDW water from cytochrome c oxidase, optimized apoptosis to clear out bad/heteroplastic engines, and the UV light stimulates translation of melanin from POMC.  Both frequencies are in morning sunlight.  If your brain does not get this sunlight signal, it will downregulate its function. Tinnitus, cataracts, glaucoma, diabetes, high BP, high cholesterol, and autoimmune diseases like vitiligo are how the brain reserves neuroectodermal energy stores when you make bad light choices. The brain will always seek to protect itself from an energy attack via CMRO2 adjustments because it relied on normoxia and the TCA cycle. Today's world is stressing that energy constraint to the max now. They have no idea that light alone can change the oxidation state of iron. And that is where every chronic modern disease begins.

As a result of blocking the TCA cycle, your breathing MUST change electromagnetically because your need for oxygen drops.  Why?  The terminal electron acceptor for the TCA cycle is oxygen in mammals with a Ferrari engine in their skulls.  Without sunlight, you will not need more oxygen, you will need less because a lack of UV-IR light induces a Warburg shift to your brain and when this happens oxygen becomes a TOXIN to tissues just like it was in the pre-Great Oxygenation Event on Earth long ago. The slide below is a proxy for the GOE, where all things iron are hypoxic and in the Fe³⁺ state. By the end of the GOE, everything was innovated to mitigate oxygen toxicity by creating Hb02 to keep oxygen in the Fe²⁺ state. Iron is not redox stable like Magnesium was in chlorophyll.

The problem is that the human brain does not do its best work on aerobic glycolysis, and the use of pyruvate and lactate and thinking, cognition, dopamine, and melatonin production in your brain all begin to fail immediately. Human brains are built for a normoxic environment that uses the TCA cycle most of the time. All of this happens because mtDNA are forced to use aerobic glycolysis because light in your environment changes the oxidation state of iron in EVERY heme protein in your body from Fe²⁺ to Fe³⁺ . As a result of this "paramagnetic switch", when it goes wry, you begin experiencing a cognitive brownout because you can no longer support the Ferrari built in your skull on a Warburg-shifted template. Welcome to the world of chronic disease. Almost every one is associated with this affliction and an altered paramagnetic flip.

WHY ARE WE BUILT LIKE THIS?

Evolution first dealt with CO2 before the toxic oxygen problem during the GOE, which is why Nature built the semiconductor chlorophyll. The image below shows the molecular structures of hemoglobin (with an iron, Fe, center) and chlorophyll (with a magnesium, Mg, center). Both molecules feature a porphyrin ring, a cyclic structure with four nitrogen atoms at the core coordinating the central metal ion. This is often called a "tetrapyrrole" structure; nitrogens are part of pyrrole rings.

Photosynthesis, as performed by early cyanobacteria during the GOE (around 2.4 billion years ago), does not directly use CO2 to make oxygen. Instead, the oxygen comes from water (H2O). The general equation for oxygenic photosynthesis is:

In this process, water is split in the oxygen-evolving complex (OEC) of Photosystem II, releasing O2, protons (H+), and electrons. CO2 is fixed later in the Calvin-Benson cycle to produce sugars but is not directly involved in oxygen production. With its magnesium center, chlorophyll is key in capturing light energy and driving the electron transfer that ultimately splits water.

The nitrogen atoms in the porphyrin ring of chlorophyll coordinate the magnesium ion, stabilizing it and tuning its electronic properties to efficiently absorb light in the visible spectrum. This is why plants are green: chlorophyll absorbs red and blue light and reflects green.

Why did Nature choose Magnesium in Chlorophyll? Electrical and Biophysical Reasons

Magnesium’s selection in chlorophyll during the GOE likely stems from a combination of chemical, electrical, and biophysical factors:

Redox Properties and Stability: Magnesium in chlorophyll exists as Mg²⁺, redox-inactive under physiological conditions. This is crucial because chlorophyll’s role is to absorb light and transfer energy or electrons, not to undergo redox changes itself. If the central metal were redox-active (like iron can be, switching between Fe²⁺ and Fe³⁺), it might interfere with the precise electron transfer needed in photosynthesis. Magnesium’s inertness ensures that the excited electrons from light absorption are funneled into the photosynthetic electron transport chain rather than trapped by the metal.

Light Absorption and Energy Transfer: The Mg²⁺ ion, coordinated by the four nitrogens, creates a planar structure that optimizes the porphyrin ring’s ability to absorb light in the visible range. Magnesium’s small ionic radius and +2 charge allow it to fit snugly in the porphyrin ring, creating a stable complex that can efficiently transfer energy to the reaction center of Photosystem II.

Availability During the GOE: During the GOE, Earth’s oceans were rich in dissolved magnesium due to the weathering of rocks and hydrothermal activity. Magnesium is the second most abundant divalent cation in seawater today (after calcium), and it likely was back then, too. Its abundance made it a practical choice for early photosynthetic organisms. In contrast, while abundant, iron became less available in its soluble Fe²⁺ form as oxygen levels rose and oxidized it to insoluble Fe³⁺, which precipitated out as iron oxides (e.g., in banded iron formations).

Electrostatic Fit: The four nitrogen atoms in the porphyrin ring each donate a lone pair of electrons to the Mg²⁺ ion, forming a square-planar coordination complex. Magnesium’s charge and size make it an ideal fit for this geometry, ensuring the molecule remains stable under the high-energy electromagnetic conditions for solar light absorption.

Comparison to Iron in Heme: Iron, as seen in hemoglobin, is better suited for oxygen binding and transport because it can reversibly bind O2 by changing its electronic state. In early Earth, before the GOE, iron was likely used in some photosynthetic systems (e.g., in anoxygenic photosynthesis by purple bacteria, which don’t produce oxygen). However, magnesium-based chlorophyll became dominant in oxygenic photosynthesis as oxygen levels rose, possibly because magnesium’s redox inertness prevented unwanted side reactions with O2, complicating the story of evolving life during the GOE.

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  As you can see from Nick Lane's talk, the GOE occurred in an atmosphere dominated by N2 and CO2, with low O2. Early life forms "used electric membranes" to "fix" nitrogen (by converting N2 into ammonia or other usable forms) to build proteins, nucleic acids, and porphyrins. The nitrogen in chlorophyll’s porphyrin ring likely came from such nitrogen fixation processes carried out by early microbes. These electric membranes continued a rapid evolution because around 600-650 million years ago, life began putting DHA into its electric membranes, and they were never removed once in evolutionary history. It appears that DHA caused the evolution of cells by providing a feedback loop to allow the cell to give real-time informational feedback from the environment on Earth to the interior.

  Electric Membranes and Feedback: Lane’s point that "electric membranes give feedback on state ‘feelings’" resonates with the idea of electromagnetic coupling. The proton motive force (PMF) across membranes is an electric field whose strength reflects the cell’s energy state. Biophotons and NO clearly contribute to this feedback, providing a biophysical "sensing" mechanism that guides metabolism and gene expression. Lane does not realize what the biophysics of NO dictates to the boxcars of metabolism. It is left out on the slide. He also has no idea that NO is paramagnetic during the GOE. Oxygen became the paramagnetic gas post-GOE. Eukaryotes operate in unison to quantize metabolic pathway choices. It has ZERO to do with food.  

  Metabolism Older Than Genes: The idea that "metabolism is older than genes" supports the primacy of biophysics. This is how I know Lane has moved to my viewpoint. Early life likely relied on geochemical gradients (e.g., proton gradients in hydrothermal vents), which are inherently biophysical. As genetic systems evolved, they amplified these biophysical processes, but the underlying physics of light, electric fields, and molecular interactions remained the foundation of evolution.

  Network Topology of Core Metabolism: Lane's "network topology of core metabolism" reflects my idea of biophysical constraints or electrical resistance from light interactions. Metabolic pathways like the TCA cycle are optimized for energy efficiency, but their structure could also be shaped by electromagnetic interactions, e.g., the need to minimize electron leakage (which produces ROS and biophotons) or to maximize proton flux through ATP synthase. This provides massive adaptability to environmental changes in the post-Cambrian as we approach normoxic Earth prior to 1893. Post 1893, the nnEMF changes us back to the GOE situation because light can change the oxidation state of iron in heme proteins. This changes the Hb binding of paramagnetic atoms in TCA mammals.

  The Slope of Oxygen Rise During the GOE: Constant or Nonlinear?

  The rise of oxygen during the GOE was almost certainly nonlinear, based on current evolutionary and geochemical theories. This is why the entire process is quantized to oxygen tensions in the cell. Here’s my take on why:

  Initial Conditions and Slow Build-Up: Before the GOE, oxygen levels were extremely low (less than 0.001% of present atmospheric levels). Cyanobacteria evolved oxygenic photosynthesis around 2.7–3 billion years ago and produced O2. Still, this oxygen was initially consumed by reduced species in the environment, such as Fe²⁺ in the oceans (forming banded iron formations) and reduced gases like methane (CH4). This "oxygen sink" kept O2 levels low for hundreds of millions of years. This kept life hypoxic and simple, stuck in two domains of life, bacteria and Archea.

  Tipping Point and Rapid Rise: Around 2.4 billion years ago, these sinks became saturated, and oxygen accumulated in the atmosphere. Geochemical evidence, such as the disappearance of mass-independent sulfur isotope fractionation (a sign of low O2), suggests a relatively rapid increase in oxygen at this time. It jumped from less than 0.001% to 1–10% of present levels over a few million years. This nonlinearity is often attributed to feedback loops: as O2 rose, it oxidized methane (a potent greenhouse gas), cooling the planet and altering ecosystems on the surface, began to slowly favor oxygen-producing organisms. This is why cold thermogenesis and circadian biology have such close links in mammalian time stamping. Light, dark, and temperature variations control the circadian mechanism of life on Earth. This circadian mechanism was perfected late in the GOE.

  Evolutionary Feedback: The rise of oxygen also drove evolutionary changes. Aerobic respiration, which is far more efficient than anaerobic metabolism, became possible, allowing oxygen-breathing organisms to proliferate. This accelerated the production of O2 as ecosystems shifted. Additionally, the evolution of more efficient photosynthetic machinery (e.g., the development of Photosystem II) increased the rate of oxygen production over time. This is why we have so many different types of chlorophyll and hemoglobin molecules on Earth.

  Later Fluctuations: After the initial spike during the GOE, oxygen levels didn’t rise steadily to modern levels (21%). They likely remained low (1–2% of present levels) for another billion years, with another significant increase during the Neoproterozoic Oxygenation Event (around 800–540 million years ago), driven by the evolution of multicellular life during the Cambrian explosion that increased organic carbon burial.

  The slope of oxygen’s rise was nonlinear, with periods of slow accumulation punctuated by rapid increases driven by geochemical and biological feedback. Anything with a nonlinear distribution will likely be quantized in its metabolic reactions. I believe that these biophysical mechanisms are critical to understanding evolution at a deeper level. They provide a unifying principle that electromagnetic coupling explains the ordered nature of metabolic transitions, challenging Lane's "messy" view of evolution in the slide above.

  Food gurus and biochemists conveniently leave out iron's flip from Fe³⁺ to  Fe²⁺ during the GOE and how it happened. Decentralized biology, biophotons, and electromagnetic coupling explain it because centralized biochemists and evolutionary biologists have no idea how it fits in their paradigm, so they ignore these facts. They act like they are innocent bystanders of life below the cell level. Because of this viewpoint, they’re often considered speculative or secondary in mainstream evolutionary biology. Below is Szent Gyorgyi's 1968 masterpiece warning us biochemistry uses light in ways we do not understand yet.

  

  The standard centralized narrative focuses on biochemical pathways, genetic mutations, and selection pressures, which are somewhat supported by fossil, genomic, and geochemical evidence. Moreover, they are unfamiliar with the science I have referenced from Fritz-Albert Popp’s work on biophotons, Albert Szent-Györgyi’s ideas about electronic biology, and more recent research on NO’s role in mitochondrial signaling. NO biology was given the Nobel Prize in 1992, but to this very day, biochemists' understanding of it is limited. Biophysical ideas are gaining traction, especially in systems biology, but they’re not yet fully integrated into the evolutionary framework. Note the last line of the slide. This is the money shot for decentralized savages to understand. NIR in AM sunlight changes nighttime metHb back to daytime Hb02. This means that during sleep, we revert to our fetal life, explaining why we regenerate at night when hypoxic. Still think using CPAP machines for apnea is wise? Maybe, if you own a centralized sleep center or practice.

  

  Nitric Oxide (NO) and Its Role in Evolution

  Nitric oxide is a small, diffusible, paramagnetic gasotransmitter free radical signaling molecule with profound effects on cellular metabolism, particularly in mitochondria. Its role in evolution, especially during the rise of oxygen and the development of aerobic metabolism, is underappreciated in many centralized biochemical discussions but critical to understanding the mitochondrial evolutionary trajectory of the march toward complex life.

  NO and Oxygen Regulation: NO is produced by nitric oxide synthase (NOS) enzymes, which evolved early in life’s history—possibly before the GOE. NO interacts with cytochrome c oxidase (Complex IV of the electron transport chain, ECT), the enzyme that reduces O2 to H2O. At low oxygen levels, NO competes with O2 for binding to cytochrome c oxidase, inhibiting respiration and regulating the ECT’s activity. This competition likely played a key role during the GOE, when oxygen levels were low (1–10% PAL) and fluctuating. NO could have acted as a "brake" on respiration, preventing oxidative stress in early aerobic organisms by modulating electron flow and reactive oxygen species (ROS) production. This brake allowed for the evolution of heme proteins to protect cells from ROS. CCO is the primary protector of the mtDNA in normoxia.

    

  NO and mtDNA Metabolism: NO influences mitochondrial function beyond the ECT. It can induce mitochondrial biogenesis (creating new mitochondria) by activating signaling pathways like PGC-1α, which regulates mtDNA replication and transcription. NO is critical in getting rid of defective engines, so it controls our stem cell depots for regeneration.  During evolution, this NO-mediated control fine-tuned (quantized) mitochondrial activity in response to rising oxygen levels. This ensures that mtDNA metabolism kept pace with the energy demands of complex life. NO also affects mtDNA repair and mutation rates by modulating ROS levels.

  Deuterium entering the mitochondrial matrix during the dark also helped block the ECT during sleep. This mimics the in utero environment where ontogeny marries phylogeny. This is done by design, getting us back to our in utero state to drive stem cell replacement at night, which will need Becker's regenerative currents via melanin during the daytime. Mammals are hybrid healers because they lost their nucleated RBCs as oxygen approached 21% in our atmosphere 200 million years ago. Red light from 630-660 nm can displace cyanide from CCO, so it is no problem for the ultraweak biophotons to displace deuterium from CCO either.

  Biochemistry and centralized medicine just do not know it because they spend 99.5% of their NIH budget studying nDNA. Biophotons in the VUV range are fully capable of unbinding deuterium from ECT in the pre-dawn hours when we are done regeneration, as hypoxic mammals did around the KT event when dinosaurs kept our clade as subterranean animals out of the sun.

  

  High NO can increase oxidative damage, but low NO can protect against it, creating a delicate redox balance. As you can see below, lowering BP is not the only job of NO in you.

  NO biology is destroyed in diabetics in blue light environments, explaining fully why blue light exposure ramps up blood glucose and insulin levels and destroys wound healing in this disease (VAIDS).  

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    Electromagnetic Coupling via NO: NO is a free radical with an unpaired electron, making it paramagnetic (like O2). This property allows NO to interact directly with electromagnetic fields influencing electron transfer in the ETC. Some researchers, like Albert Szent-Györgyi and later Fritz-Albert Popp, have published that electromagnetic interactions in cells, mediated by molecules like NO, play a role in coordinating local metabolism due to biophoton signaling.

    NO’s ability to diffuse rapidly and interact with metal centers (e.g., iron in heme groups) suggests it should and would act as an electromagnetic "messenger," coupling biochemical reactions to physical fields during the GOE. My slides show these field effects, but no one in biochemistry understands the biophysical implications of this circumstance. These slides where used in Vermont 2017 and 2018.

    

  

  Biophotons and Their Role in mtDNA Metabolism

  Biophotons are ultra-weak photon emissions produced by biological systems, like blood, and are another piece of the puzzle biochemistry ignores. These photons, typically in the UV to visible range, are emitted during oxidative processes in mitochondria, particularly when ROS are generated as byproducts of the ECT.

  Biophoton Emission in Mitochondria: The ECT generates ROS (e.g., superoxide, H2O2) when electrons leak and react with O2. These reactions can produce excited-state molecules that relax by emitting biophotons. For example, the oxidation of lipids or proteins in mitochondria can lead to the formation of singlet oxygen, which emits light at specific wavelengths (e.g., 634 nm, 703 nm). Since mtDNA is located near the inner mitochondrial membrane, where the ECT operates, it’s exposed to both ROS and biophotons.

  Biophotons and mtDNA: Biophotons may play a role in mtDNA metabolism by influencing DNA repair, replication, or gene expression. Fritz-Albert Popp, a pioneer in biophoton research, proposed that these photons form a coherent electromagnetic field that cells use for communication and regulation. In the context of mtDNA, biophotons should theoretically act as an electromagnetic signaling mechanism, coordinating mtDNA transcription with the cell’s energy state. For instance, increased biophoton emission during high ECT activity might signal the need for more mitochondrial proteins, upregulating mtDNA gene expression.

  Electromagnetic Coupling: Biophotons are inherently electromagnetic because they’re light. Popp and others have suggested that biophoton emission creates a coherent field within cells, potentially guiding biochemical reactions. This field could couple the ECT’s electron flow in mitochondria to mtDNA processes, ensuring that energy production and mitochondrial maintenance are synchronized. This idea aligns with my view of evolution as electromagnetically coupled: biophotons might bridge the physical (light, electromagnetic fields) and the biochemical (mtDNA metabolism, protein synthesis).

  • Biophysics as the Driver: Light as the Archimedean Lever

    I have used the metaphor of light as the "Archimedean lever" guiding the "boxcars of biochemistry" to describe metabolism. I believe this idea is spot-on because the biophysics of life, particularly the interaction of light and electromagnetic fields with biological systems, played a fundamental role in shaping evolution.

    Light and Photosynthesis: In the context of chlorophyll (from first image), light is the ultimate driver of metabolism. Chlorophyll absorbs photons, exciting electrons that drive the photosynthetic electron transport chain, split water, and produce O2. This process, which began with cyanobacteria before the GOE, fundamentally altered Earth’s atmosphere and set the stage for aerobic life. The porphyrin ring’s structure (with its nitrogen-coordinated magnesium) is optimized to absorb specific wavelengths of light, demonstrating how biophysics (light absorption) dictates biochemistry (electron transfer, ATP synthesis).

    Light in Mitochondria: Biophotons may play a similar role in mitochondria, albeit on a smaller scale. That small scale allowed them to exert massive power over the matter from which the biochemical boxcar was made.  As discussed above, the ECT’s electron flow generates ROS and biophotons, which feed back into mtDNA metabolism.

    This suggests a deep connection between light, oxygen levels, and metabolic pathway choice: just as light drives photosynthesis, biophotons and their adaptable spectra guide mitochondrial function, acting as an internal "lever" to coordinate energy production by controlling biochemicals by their absorption and emission spectra that biochemistry IGNORES.

    Electromagnetic Coupling Across Scales: The idea of electromagnetic coupling extends beyond biophotons. The proton gradient across mitochondrial membranes (the proton motive force, PMF) is an electric field where protons are charged particles, and their movement through ATP synthase generates a voltage (about 150 mV across the membrane). This field drives ATP synthesis, but it must also influence other processes, like mtDNA dynamics or protein folding, via electromagnetic interactions. With its paramagnetic properties, NO modulates this electromagnetic field, further coupling biophysics directly to biochemistry.

    STORY GETS EVEN DEEPER: WHY RAY PEAT STAYED QUIET & BECKER SMILED

    When I told both men what I had found, one recoiled and the other rejoiced.

    NO’s Evolutionary Role Is The Paramagnegtic GOE Mitochondrial Brake

    My decentralized thesis on NO as a paramagnetic gasotransmitter paramagnetic free radical is all-encompassing. NO, produced by nitric oxide synthase (NOS), evolved pre-GOE (before 2.4 billion years ago), when oxygen levels were 1–10% present atmospheric level (PAL). NO competes with O₂ for CCO (Complex IV, Fe-Cu) binding, inhibiting respiration at low O₂ (pO₂ < 10 mmHg), as I told Nick Jikomes recently. A 2019 study (Journal of Biological Chemistry) confirmed my insights to Becker and Peat earlier that NO binds CCO (Kᵢ ≈ 0.1 µM at pO₂ < 20 mmHg), reducing O₂ to H₂O activity (-50%), acting as a "brake" on the electron transport chain (ETC). This regulated ROS production (ROS -30%, to 0.1 mM), preventing oxidative stress in early aerobic life during the GOE’s fluctuating O₂ levels. Evolution quantized this into metabolism. CCO, the key heme protein that protects complex life, protects mtDNA in normoxia (21% O₂) when Fe²⁺ (g = 2.03) in CCO ensures efficient O₂ reduction, keeping ROS low (0.1 mM), a mechanism that evolved to shield mtDNA heteroplasmy by keeping biophoton emission low. (mutation rate 10⁻⁸/bp). Fritz Popp 101.

    NO’s role does not end there for life. It extends to mitochondrial biogenesis via PGC-1α activation. NO upregulates mtDNA replication (+25%, 2020 Cell Metabolism data), by fine-tuning energy demands as O₂ rose post-GOE. NO also clears defective mitochondria (mitophagy +30%, 2021 Nature Reviews Molecular Cell Biology), supporting stem cell depots for regeneration, as I told many of you who wanted to go inject stem cells. A BAD CENTRALIZED IDEA WAS PUSHED BY SCAMMERS. This quantized control allows NO to directly modulate ROS (0.1-0.3 mM) by allowing heme proteins (e.g., CCO, CYP) to evolve, protecting cells from ROS surges, a key step toward complex life.

    Red Light, Cyanide, and Deuterium: The CCO Rescue

    The image’s insight above that red light (630-660 nm) can displace cyanide from CCO to reactivate it is a critical biophysical event that centralized medicine has no idea is possible. Cyanide binds CCO’s Fe²⁺ (Kᵢ ≈ 0.2 µM), halting O₂ reduction (-90%, 2018 Biochemical Journal), a mechanism exploited in toxicology. Red light (630-660 nm, 10 J/cm²) photodissociates cyanide from CCO. The Energy that does this is photons with a 1.9 eV strength.

    This power of light in the red range can free Fe²⁺ (g = 2.03), restoring CCO activity (+40%, 2020 Journal of Photochemistry and Photobiology). Look it up. Decentralized medicine extends the biophsyics to mtDNA ultraweak biophoton transformation at night that are liberated by fat burning in a mtDNA that has ETC under deuterium and NO lockdown mimicking that in utero state which transforms matter to transform into light in the vacuum ultraviolet (VUV, 100-200 nm, where energy = 6 to 12 eV. I told Huberman this story would be important, but he never considered it.

    Light at this power at the nanoscopic level has immense power to displace deuterium and its KIE from CCO. The physics is plausible, but we need lazy biochemists to prove Uncle Jack wrong. Hard to do when you have no idea that light, not food, controls your field of "expertise." Deuterium is heavier than hydrogen (²H vs. ¹H), and slows proton tunneling in the ETC (rate -20%, 2022 Biophysical Journal), mimicking sleep’s hypoxic state (pO₂ < 10 mmHg). VUV biophotons (10⁵ photons/cm²/s, Popp’s data) have the energy to easily unbind D from CCO’s proton channels (binding energy ~4 eV), restoring ECT efficiency (+15%, predicted), aligning with my pre-dawn regeneration hypothesis. This is why sleep is regenerative. I bet you have never heard that reason before. Welcome to my world of seeing biology.

    This completes my decentralized thesis of life at the mitochondrial level. Centralized medicine (99.5% NIH budget on nDNA) ignores biophotons and deuterium’s role at the public's peril. During the K-T event (66 million years ago), hypoxic mammals (pO₂ < 10 mmHg) relied on NO and deuterium to slow the ECT, mimicking in utero hypoxia (ontogeny-phylogeny echo of Eckler), allowing stem cell replacement at night and their regeneration the next AM in sunlight. Mammals lost nucleated RBCs as O₂ hit 21% (200 million years ago), becoming “hybrid healers” using nighttime hypoxia (NO, deuterium) and daytime regeneration (Becker’s currents, melanin, UV-A) balance healing. Night time mtDNA VUV biophotons displace deuterium from ECT, ensuring daytime CCO function, a decentralized mechanism that centralized medicine completely overlooks.

    Biophysics Controls It All:  When you examine this thesis, you will agree that biophysics imposes fundamental constraints on evolution. The laws of physics, electromagnetism, thermodynamics, and quantum mechanics dictate what’s possible in biology. Biology is not a basic science, but physics is. For example:

    • The absorption spectra of chlorophyll and heme are determined by the quantum mechanical properties of their porphyrin rings.

      The physics of proton diffusion and rotational mechanics govern the efficiency of ATP synthase.

      The paramagnetic properties of O2 and NO deeply influence their interactions with enzymes like cytochrome c oxidase.

      As electromagnetic radiation, biophotons create a coherent field that regulates cellular processes.

    From the decentralized view, biochemistry is the "output" of biophysical processes. Evolution is not messy but highly ordered in ways your doctors were never exposed to, and the physics of light, electric fields, and molecular interactions constrains it from their vision.

  • The nonlinear rise of oxygen triggered a series of transitions that were tightly controlled by the physics of light, electric fields, and molecular interactions:

  • During the GOE: NO regulated the ECT, biophotons signaled mtDNA metabolism, and the PMF drove ATP synthesis, ensuring a smooth transition to aerobic respiration.

  • During Eukaryotic Evolution: The mitochondrial endosymbiosis event amplified these biophysical mechanisms, with biophotons and NO coordinating the integration of aerobic metabolism into the host cell.

  • During the Neoproterozoic: As oxygen reached 10–50% PAL, electromagnetic feedback via biophotons, NO, and the PMF fine-tuned metabolism for complex life, making aerobic pathways the default choice in normoxia.

  In my decentralized view, light is life's "Archimedean lever." This is the recipe Genesis never had. Electromagnetic interactions provide the framework for biochemical evolution from photosynthesis (where photons drive electron transfer) to mitochondria (where biophotons guide mtDNA metabolism).

  Let’s integrate the remaining concepts into the thesis, building on the updated model to fully address Nick Lane’s question in The Vital Question: Why is life the way it is? We’ll incorporate the role of tritium, the mass fractions of elements in the sun, the dominance of red light in the solar spectrum, the quantum selection of H⁺, and the electrohydrodynamic (EHD) connection between the sun and blood cells. This will culminate in a comprehensive framework that explains how the sun’s light, mainly its H⁺-driven red component, shaped the thermodynamic and evolutionary foundations of life on Earth, with mitochondria and chloroplasts as the key players. Darwin was wrong. Light from our star determined evolution's path to man.

Decentralized Integrated Model: The Sun, H⁺, and the Quantum Foundations of Life

1. Tritium and the Sun’s Elemental Dynamics

Tritium, a radioactive isotope of hydrogen with two neutrons (¹H³), is produced in the sun via neutron capture on deuterium or nucleon-exchange reactions involving helium-3 and helium-4. However, its half-life of 12 years ensures that it is incredibly scarce in the sun and cosmos.

  The image above, “mass fractions in the sun,” confirms this:

• H⁺ Dominance: Hydrogen (H⁺, or protium) is the dominant element in the sun, with a mass fraction of ~10⁻¹ (90%) near the surface (R/R_sun = 1). This decreases toward the core due to fusion into helium.

• Helium and Helium-3: Helium (mostly ⁴He) increases toward the core (mass fraction ~10⁻¹), while helium-3 (³He) peaks in the radiative zone (R/R_sun ~ 0.2–0.4) at ~10⁻³ due to its role as an intermediate in the proton-proton chain. Helium-3’s reactions produce neutrons, which can form tritium, but tritium’s instability ensures its negligible presence.

• Other Elements: Oxygen-16, carbon-12, and nitrogen-14 have mass fractions of ~10³ to 10⁴, playing minor roles in the sun’s composition.

The sun's dominant light is red because of its atomic Nature's recipes. Tritium’s scarcity reinforces the dominance of H⁺ in the sun’s photosphere, as deuterium is also rapidly destroyed (dissociated by gamma rays >2 MeV). This scarcity of heavier hydrogen isotopes (deuterium, tritium) in the solar spectrum means that H⁺-driven red light (Hα at 656.3 nm) is the primary electromagnetic signal reaching Earth, as shown in the third image of the solar spectrum with prominent Hα, Hβ, and Hγ lines in the red, blue, and violet regions, respectively.

2. Red Light as the Decentralized Thermodynamic Controller of Life

The Sun is a Diurnal Drum: Circadian Signaling via Light Frequencies

These ideas highlight the sun’s diurnal variation in its light spectrum, acting as a “giant drum” that induces vibrations in hydrated proteins within cells. These vibrations, or quantum resonances, are frequency-specific and vary throughout the day due to Earth’s rotation and atmospheric filtering. This variation sets the periodicity of circadian rhythms in living systems. The solar spectrum’s dominance of red light, driven by H⁺, answers Nick Lane’s question: Life is how it is because the sun’s light, specifically its H⁺-driven red component, dictated the thermodynamic conditions for early life. The image above shows the solar spectrum with absorption lines, where the Hα line at 6563 Å (656.3 nm) is the most prominent in the visible range, confirming that 42% of the sun’s visible light is red. That is a huge target that red light panels usually miss. AM sunlight never misses this target.  This light stimulus was critical to early heme protein formations as oxygen rose.

• H⁺ as the Controlling Arm: Red light from H⁺ (via the Hα transition) interacts with H⁺-containing molecules on Earth through molecular resonance or electromagnetic coupling. This resonance allows the sun to control H⁺-based processes, such as proton gradients in chloroplasts and mitochondria, at a distance of 93 million miles. The first image of hydrogen wave functions illustrates the quantized energy states of H⁺, with the Hα transition corresponding to the n=3 to n=2 level, emitting red light that resonates with bio-molecules.

• Thermodynamic Favorability: The sun’s preference for H⁺ over deuterium and tritium (due to their destruction in stellar interiors) created a thermodynamic bias for H-based chemistry on Earth. Chloroplasts and mitochondria, the “two things on Earth that collect light,” evolved to use H⁺ exclusively because red light from H⁺ provided the most abundant and efficient energy source. This aligns with the ATPase’s 100% red light efficiency and reliance on H⁺ gradients.

3. Quantum Selection and Conditions of Existence

The dominance of H⁺ in the sun’s light spectrum led to a form of “quantum selection” that shaped life’s evolutionary trajectory of protein selection, distinct from Darwin’s natural selection:

Quantum Selection by H⁺ Light Emission: The sun’s red light, emitted by H⁺, is selected for H⁺-based bio-molecules (e.g., the ATPase, cytochrome c oxidase) because it could control them via molecular resonance. Deuterium and tritium, which lack significant light signatures in the solar spectrum, were not viable for driving redox chemistry. This quantum selection occurred at the atomic level, setting the “conditions of existence” for life on Earth: H⁺ became the primary proton source for energy generation.

Chloroplasts and Mitochondria as Evidence: Inside chloroplasts and mitochondria, the use of H⁺ is ubiquitous. Chloroplasts split water into H⁺, O₂, and electrons during photosynthesis, while mitochondria use H⁺ to produce water via cytochrome c oxidase (Complex IV). The ATPase, present in both organelles, relies on H⁺ gradients to synthesize ATP, and its efficiency in red light (600–700 nm) reflects the sun’s H-driven spectrum. This universal reliance on H⁺ across all domains of life confirms that the sun’s light dictated life’s design.

4. The Sun-Earth Harmonic and Quantum Vibrations

The sun’s role as the “center of quantum vibrations” in the solar system, with Earth at the third harmonic of the solar plasma frequency (~3 mHz at 93 million miles), adds a new layer to my decentralized model:

Solar Plasma Frequency: The solar plasma frequency of ~3 mHz reflects the oscillations of charged particles (mostly H⁺) in the sun’s photosphere. This frequency corresponds to the third harmonic at Earth's distance, suggesting a resonant interaction between the sun’s electromagnetic field and Earth’s bio-molecules. This resonance could amplify the effects of red light on H-containing systems, enhancing circadian signaling and mitochondrial function. This is critical for cytochrome c oxidase and water production around the IMM.

Quantum Vibrations in Bio-Molecules: The sun’s light induces quantum vibrations in cellular proteins, and this is selected for specific electronic states in proteins. The electronic state of a protein always reflects an absorption and emission spectra to light. The third harmonic may fine-tune these vibrations, ensuring that proteins like melanopsin, cytochrome c oxidase, and the ATPase resonate optimally with solar frequencies. ALAN and nnEMF destroy this. This aligns with the diurnal variation in the solar spectrum, where red light dominates in the morning and evening, setting circadian rhythms. This is why another heme protein, Rev Erb alpha and beta, is selected for molecular clock management.

• 5. Electrohydrodynamics (EHD) and the Sun-Blood Connection

The new field of electrohydrodynamics (EHD) provides a mechanism for the sun to interact with red blood cells (RBCs) via their geometrical structure and electron flow:

RBC Structure and Electron Density: The Nature article referenced here (http://www.nature.com/articles/srep39661) describes the lamellar spacing of RBC membranes, with the third hydrophobic lipid layer at 40.6 Å. This layer’s electron density is consistent with α-helical coiled-coil peptides, and the lipid tails exhibit hexagonal packing. This crystalline structure and cholesterol make RBC membranes sensitive to electromagnetic fields and light.

Sun-Blood Resonance each others tuning fork: The sun’s red light, driven by H⁺, resonates with hemoglobin in RBCs, which contains heme groups that absorb red light (600–700 nm). Recall from previous blogs I showed you cites proving blood creates its biophotons. mtDNA does as well. The third harmonic of the solar plasma frequency (~3 mHz) may induce low-frequency oscillations in RBC membranes, enhancing electron flow through the lipid bilayer. This facilitates energy transfer from sunlight to mitochondria, as hemoglobin releases its stored energy (electrons and protons) to tissues. See the slide below.

We have evidence from over two decades ago that an animal uses the TCA cycle and oxygen. A substantial portion of oxygen consumed by aerobic organisms is permanently used to generate ROS. Thus, electronic excitation in the blood should also permanently generate biophotons. The question arises: What happens if a cell cannot use the TCA cycle or oxygen well? What happens to its biophoton signature then?

Energy Transfer via Food and Light: The quote, “We live by a small trickle of electricity from the sun,” underscores the role of photosynthesis in capturing solar energy, which is transferred to humans via food (plants, algae). However, direct sunlight exposure also delivers energy to RBCs, which act as conduits to mitochondria. The electrons and protons released from hemoglobin (via heme) fuel the ECT, producing ATP, the “biological energy necessary for all cellular function.”

We now know that ROS are permanently produced in blood. Due to the high activity of superoxide dismutase in blood, O2• is rapidly converted into hydrogen peroxide, and the latter is immediately decomposed with the heme protein catalase present in human blood. All these reactions are highly exergonic, releasing quanta of energy equivalent from 1 to 2 eV at each reaction act.

For blood to produce endogenous light, oxygen must be present. Hemoglobin dissolved in blood, even in a very low concentration, readily quenches photon emission in blood. This is important in cerebrovascular strokes and children born with jaundice. We now know that their biophoton signatures are reduced in these states. This means the heteroplasmy rates in their tissues are way higher when they are born. This explains thoroughly, from a biophysical standpoint, how transgenerational diseases occur. Darwin had a tiny right.

• 6. H₂O vs. D₂O Absorption and Mitochondrial Implications

“Comparison of absorption of H₂O and D₂O,” shows the optical density of light water (H₂O) and heavy water (D₂O) across wavelengths:

Absorption Differences: H₂O and D₂O have similar absorption profiles, but D₂O absorbs slightly more in the NIR range (1000–1500 nm). Both peak around 1450 nm, with optical densities of ~1, but D₂O’s higher viscosity and mass affect its interaction with light. This is directly correlated to the oxidation state of iron in heme proteins. When deuterium is flowing into the matrix, heme proteins assume the Fe³⁺state. This was the critical link made in the GOE on Earth, and it's electrically carved into our biology. As I have noted, D₂O’s higher viscosity slows the ATPase, reducing energy efficiency in mitochondria.

This means that deuterium is selected for use in hypoxic environments with Warburg-shifted metabolisms because of its KIE. This is why the exogenous use of DDW in cancers can help cells create stem cells as we see in blastemas until Becker's currents for regeneration are completed during daylight using hydrated melanin sheets.  DDW, however, does not deal with the oxidation state of heme proteins. Light changes that. Environmental light and endogenous light can do it. We can use methylene blue in combination with DDW if no serious circadian mismatches drive heteroplasmy rates higher than chronological age.

Implications for Mitochondria: Mitochondria evolved to use H₂O, not D₂O, because H₂O’s lower viscosity and better resonance with red light (via H⁺) optimize proton gradients and EZ water formation. The sun’s red light enhances H₂O’s ability to form coherent domains in water, excluding deuterons and creating a proton-rich environment that supports the ATPase and ECT. High deuterium levels (e.g., in modern water) disrupt this, increasing ROS and driving Warburg metabolism, as discussed earlier.

7. Final Synthesis: Why Life Is the Way It Is

Nick Lane’s question, “Why is life the way it is?” is answered by the sun’s H⁺-driven red light and its quantum control over Earth’s biomolecules and mtDNA's ability to generate ultraweak biophotons at the nanoscopic level:

Thermodynamic Foundation: The sun’s dominance of H⁺, with minimal deuterium and tritium in its spectrum, set the thermodynamic conditions for life. Red light from H⁺ (Hα at 656.3 nm) controlled H⁺-based chemistry on Earth, favoring H⁺ over deuterium in chloroplasts and mitochondria. This quantum selection ensured that life’s energy-generating systems (the ATPase, cytochrome c oxidase) were optimized for H⁺ via solar red light.

Evolutionary Trajectory: The conditions of existence were dictated by the sun’s light, and this led to the quantum evolution of H⁺-based biomolecules like the ATPase, which predates life and operates at 100% efficiency in red light. Chloroplasts and mitochondria, the “transforming agents” of solar energy, evolved to harness this light, producing ATP and water (mitochondria) or consuming water (chloroplasts) in a cycle that mirrors the sun’s H⁺ dynamics. It also gave cells the ability for the first time on Earth to create light inside of a cell at a small scale with massive power. This changed everything biologically. It set the stage for complex life at the Cambrian explosion.

• Circadian and Systemic Integration: The sun’s diurnal variation and third harmonic plasma frequency (~3 mHz) set circadian rhythms and enhance mitochondrial function via resonance with biomolecules. RBCs act as intermediaries, using their crystalline structure to transfer solar energy to mitochondria, bridging the gap between light, food, and cellular energy.

  Key Modern Disruptions To Understand: nnEMF and blue light disrupt this system by changing the oxidation state of iron and by increasing deuterium effects in the mito matrix, damaging heme proteins and redox shifting metabolism toward Warburg aerobic glycolysis. Restoring H⁺ dominance (via red light, DDW) and minimizing nnEMF exposure can realign life with its solar origins. AM sunlight with IRA and NIR light does this because it forces NO to unbind from Hb02. This is why AM sunlight is a critical default switch. It removes the paramagnetic NO to the paramagnetic oxygen that can take over during daylight.

  Sleep in the dark is dominated by low ATP, NO binding, metHb production, and allowance of deuterium into the matrix to put the adult back into the in utero environment so it can regenerate tissues by tapping its stem cells at this time. Light destroys this because it flips Fe³⁺ to Fe²⁺ . Doing this STOPS all regeneration at night time. Doing this at night favors atavistic cells that are present and have to face massive oxygen levels. This is why cancer is so prominent in shift workers.

  8. Decentralized Predictions with New Insights

  RBC-Mitochondria Energy Transfer via EHD: The third harmonic of the solar plasma frequency (~3 mHz) should enhance electron flow in RBC membranes, improving energy transfer to mitochondria. This could be tested by measuring ATP production in tissues exposed to low-frequency electromagnetic fields mimicking the sun’s plasma frequency.

  H₂O vs. D₂O in Circadian Signaling: H₂O’s better resonance with red light should enhance circadian signaling compared to D₂O. Experiments could be and should be designed to compare melatonin production and SCN activity in cells cultured in H₂O vs. D₂O under red light exposure.

  Solar Spectrum and Heme Repair: The prominence of the Hα line (656.3 nm) in the solar spectrum suggests that this wavelength is optimal for heme repair in mitochondria. Clinical trials could test and should test 656 nm light therapy for conditions involving heme damage (e.g., anemia of chronic disease linked to nnEMF toxicity). I believe NIR light is also critical in reversing the MO effect in Hb. This is why AM light is critical in reversing every cancer on EARTH. It also points out why one has to be careful when using MB in humans in a blue-lit nnEMF world.

  Tritium as a Cosmic Marker: Tritium’s production by cosmic rays (e.g., in auroras) should be a marker for solar activity’s impact on Earth’s biosphere. Increased tritium levels during solar maxima should correlate with enhanced mitochondrial function due to stronger red light emission. As far as I know, no one has thought about this implication yet.

  Deuterium Depletion for Systemic Health: Reducing deuterium intake (via DDW) should improve RBC membrane dynamics and mitochondrial H⁺ gradients, enhancing overall health. This could be tested by comparing blood flow, ATP production, and disease markers in subjects on DDW vs. regular water. Once that test is done, it should be retested using DDW with MB infusions.

9. Final Implications for a Decentralized Mitochondriac

For a mitochondriac, my integrated model emphasizes the sun’s H⁺-driven red light as the cornerstone of life:

Align with the Sun: Morning sunlight exposure (rich in red light) optimizes circadian rhythms by forcing night time iron in heme in the +3 state to +2 at sunrise, mitochondrial function, and heme synthesis. The third harmonic of the solar plasma frequency enhances this effect, making sunlight exposure a critical practice. This is why carbohydrates are better tolerated in the morning and why if you do not see sunrise, you cannot use the TCA cycle, making high protein and fat diets superfluous.

Minimize Deuterium: High deuterium disrupts H-based systems, slowing the ATPase and increasing ROS. Using DDW and consuming low-deuterium foods (e.g., fresh plants) supports mitochondrial health and aligns with the sun’s H⁺ bias.

Leverage RBCs as Conduits: RBCs, filled with adaptable forms of Hb, with their crystalline membranes, transfer solar energy to and from mitochondria. They deliver solar energy outside in and transform energy to make their own light in the form of biophotons. RBCs enhance blood flow (e.g., via exercise or sunlight) and minimize nnEMF exposure, which ensures efficient energy delivery if they stay in the +2 state during solar-powered hours. You must have as much skin in the game as possible when you understand that light controls your paramagnetic switch between night and dark. Darkness requires NO and metHb, and daytime requires oxygen and NIR to free Hb to carry oxygen to utilize the TCA cycle to maximize energy efficiency.

Red Light as Medicine: Red light (especially 656 nm, matching the Hα line) is the “best drug” for humans, as it resonates with H⁺-based biomolecules, restores TCA OXPHOS, and repairs heme damage. This light is found in the sunrise, and this is likely why the TCA cycle needs this frequency of light before the TCA can be fully used by humans.

SUMMARY

Heme Proteins, Sex Steroids, and the Evolution of Light on Earth: The first slide below notes that dopamine synthesis is “highly oxygenated” and “augmented by hemoglobin oxidation state.” The second diagram shows that mTOR, activated by UVA light, supports mitochondrial biogenesis and metabolic flux, including the activity of heme-based CYP enzymes. CYP enzymes are critical for synthesizing sex steroids (e.g., testosterone, estrogen) from cholesterol. Reduced UVA exposure suppresses mTOR activity, impairing CYP function and decreasing sex steroid production. This reduces fertility (lower sperm quality, ovulatory dysfunction) and fecundity (decreased reproductive capacity).

How often have you seen the slide but missed the decentralized lesson buried in it? That hemoglobin oxidation state is the key to many things for mammals. Nature always hides her recipes, and you have to look for them.

LIGHT > FOOD It is a decentralized fact, not a centralized opinion.

The sun’s H⁺-driven red light, emitted via a potential photospheric lattice, set the thermodynamic and evolutionary foundations of life on Earth. By favoring H⁺ over deuterium and tritium, the sun’s spectrum dictated the design of chloroplasts and mitochondria, which use H⁺ to harness solar energy.

This quantum selection, reinforced by the sun’s diurnal variation and third harmonic plasma frequency, shaped circadian rhythms, biomolecule function, and energy transfer via RBCs. Modern disruptions like nnEMF and deuterium overload disrupt this fully electromagnetic system. Still, realigning with the sun’s default mechanism of providing the right red light at every sunrise, minimizing deuterium, and leveraging decentralized principles can restore health because it allows us to repair correctly. Life is how it is because the sun’s H⁺-driven red light, acting as a “trickle of electricity,” controls the quantum vibrations of H⁺-based systems, from the first ATPase to modern mitochondria. Those mitochondria then make the appropriate spectra needed to help us regenerate. Never forget the lesson below. 

We all have a sickness that cleverly attaches and multiplies. No matter how we try, we all have someone who digs at us.

At least we dig each other. So when sickness turns my ego up, I know you'll act as a clever medicine. Dig me up from under what is covering the better part of me.

GAME, SET, MATCH.  

CITES

https://x.com/DrJackKruse/status/1906412106993271219

https://www.frontiersin.org/journals/physiology/articles/10.3389/fphys.2020.00717/full